웹Human breast cancers referred to as “basal-like” are of interest because they lack effective therapies and their biology is poorly understood. The term basal-like derives from studies … 웹2024년 7월 13일 · In contrast, microvessel proliferation and the GMP vascular phenotype did not predict response but were instead associated with aggressive tumor features, including …
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웹2010년 4월 28일 · Definitions of basal-like breast cancer phenotype vary, and microarray-based expression profiling analysis remains the gold standard for the identification of these … 웹Non-basal-like tumors occupying near half of TNBC have been a confounding component to identify the true benefit of platinum agents for patients with basal-like tumors. Further … chugoku marine paints singapore
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웹Basal-Like. Of all breast cancer subgroups, basal-like breast cancers (BLBCs) have the worst clinical outcome. They represent 15–20% of breast cancers and are characterized by an … 웹Little is known about the development of basal-like breast tumors. The identification of possible precursors of BLBCs is important to gain insight into tumor genesis and to … The basal-like carcinoma is a recently proposed subtype of breast cancer defined by its gene expression and protein expression profile. Breast cancer can be divided into five molecular subtypes, including luminal subtype A, luminal subtype B, normal breast-like subtype, HER-2 overexpression subtype) and … 더 보기 BLBC is more common among young and premenopausal women in Africa and African Americans. Large sample studies based on immunohistochemistry showed that the average age of BLBC patients is 47.7 to 55 years old. … 더 보기 The most common histopathological type is invasive ductal carcinoma. It can also be metaplastic carcinoma, medullary carcinoma and adenoid cystic carcinoma, with high grade, high … 더 보기 Although tumors are often larger and of later stage, basal-like subtypes are more sensitive to anthracycline-based neoadjuvant chemotherapy than luminal breast cancers. Yet, despite initial chemosensitivity, patients with basal-like subtypes have worse … 더 보기 Studies demonstrate that BLBC has a high mitotic index and proliferation ratio. EGFR promotes cell proliferation by activating Ras/MAPK/MAPK pathways. BLBC is characterized by low … 더 보기 chukka boots hombre